Survey on the Recent Advances in 4-Hydroxyphenylpyruvate Dioxygenase (HPPD) Inhibition by Diketone and Triketone Derivatives and Congeneric Compounds: Structural Analysis of HPPD/Inhibitor Complexes and Structure–Activity Relationship Considerations
Author:
Affiliation:
1. Department of Biotechnology, Chemistry and Pharmacy − Department of Excellence 2018-2022, University of Siena, via Aldo Moro 2, I-53100 Siena, Italy
Funder
Ministero dello Sviluppo Economico
Ministero dell'Istruzione, dell'Universit? e della Ricerca
Publisher
American Chemical Society (ACS)
Subject
General Agricultural and Biological Sciences,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jafc.2c02010
Reference65 articles.
1. Inhibition of 4-Hydroxyphenylpyruvate Dioxygenase by 2-(2-Nitro-4-trifluoromethylbenzoyl)-cyclohexane-1,3-dione and 2-(2-Chloro-4-methanesulfonylbenzoyl)-cyclohexane-1,3-dione
2. The Mode of Action of Isoxaflutole II. Characterization of the Inhibition of Carrot 4-Hydroxyphenylpyruvate Dioxygenase by the Diketonitrile Derivative of Isoxaflutole
3. Molecular insights into the mechanism of 4‐hydroxyphenylpyruvate dioxygenase inhibition: enzyme kinetics, X‐ray crystallography and computational simulations
4. Structural Studies of β-Diketones and Their Implications on Biological Effects
5. 4-Hydroxyphenylpyruvate Dioxygenase and Its Inhibition in Plants and Animals: Small Molecules as Herbicides and Agents for the Treatment of Human Inherited Diseases
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