1. Department of Medicinal Chemistry and Biology, GlaxoSmithKline, 25−27 Avenue du Québec, 91951 Les Ulis, France, Computational and Structural Sciences, Department of Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, GunnelsWood Road, Stevenage, Hertfordshire SG1 2NY, United Kingdom, Department of Medicinal Chemistry, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, United Kingdom, and Departments of Renal and Urology Research, GlaxoSmithKline Pharmaceuticals, King of Prussia,...