Diastereoselective Synthesis of α,α-Disubstituted γ-Carboxypyroglutamates via Sm(III)−Azomethine Ylide Cycloadditions

Author:

Alvarez-Ibarra Carlos1,Csákÿ Aurelio G.1,López de Silanes Isabel1,Quiroga M. Luz1

Affiliation:

1. Departamento de Química Orgánica I, Facultad de Química, Universidad Complutense, 28040 Madrid, Spain

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Reference57 articles.

1. Bridges, R. J.; Geddes, J. W.; Monaghan, D. T.; Cotman, C. W. InExcitatory AminoAcids in Health and Disease; Lodge, D., Ed.; Wiley:  New York, 1988; p 321.

2. Total Synthesis of (+)-Lactacystin

3. Patel, S.; Chapman, A. G.; Millan, M. H.; Meldrum, B. S. InExcitatory Amino Acidsin Health and Disease; Lodge, D., Ed.; Wiley:  New York, 1988; p 353.

4. Protective effect of N-methyl-D-aspartate antagonists after focal cerebral ischemia in rabbits.

5. Conantokin-T. A gamma-carboxyglutamate containing peptide with N-methyl-d-aspartate antagonist activity.

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