AM-8553: A Novel MDM2 Inhibitor with a Promising Outlook for Potential Clinical Development-Reference-Cited by-同舟云学术

AM-8553: A Novel MDM2 Inhibitor with a Promising Outlook for Potential Clinical Development

Published:2012-05-24 Issue:11 Volume:55 Page:4934-4935
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bernard Denzil¹,Zhao Yujun¹,Wang Shaomeng¹

Affiliation:

1. Departments of Internal Medicine, Pharmacology, and Medicinal Chemistry, University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan 48109, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm3007068

Reference9 articles.

1. Live or let die: the cell's response to p53

2. The p53-mdm-2 autoregulatory feedback loop.

3. Structure of the MDM2 Oncoprotein Bound to the p53 Tumor Suppressor Transactivation Domain

4. MDM2 inhibitors for cancer therapy

5. Targeting the MDM2-p53 Interaction for Cancer Therapy

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