Development of a Dynamic Kinetic Resolution for the Isolation of an Intermediate in the Synthesis of Casopitant Mesylate: Application of QbD Principles in the Definition of the Parameter Ranges, Issues in the Scale-Up and Mitigation Strategies-Reference-Cited by-同舟云学术

Development of a Dynamic Kinetic Resolution for the Isolation of an Intermediate in the Synthesis of Casopitant Mesylate: Application of QbD Principles in the Definition of the Parameter Ranges, Issues in the Scale-Up and Mitigation Strategies

Published:2010-07-08 Issue:5 Volume:14 Page:1162-1168
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Bravo Fernando¹,Cimarosti Zadeo¹,Tinazzi Francesco¹,Smith Gillian E.¹,Castoldi Damiano¹,Provera Stefano¹,Westerduin Pieter¹

Affiliation:

1. GlaxoSmithKline R&D, Chemical Development, Analytical Chemistry, Via Fleming 4, Verona, Italy

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op100121s

Reference32 articles.

1. Recent developments in dynamic kinetic resolution

2. Crystallization-Induced Diastereomer Transformations

3. Asymmetric Synthesis of Active Pharmaceutical Ingredients

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