Structure-Based Design of a Novel, Potent, and Selective Inhibitor for MMP-13 Utilizing NMR Spectroscopy and Computer-Aided Molecular Design-Reference-Cited by-同舟云学术

Structure-Based Design of a Novel, Potent, and Selective Inhibitor for MMP-13 Utilizing NMR Spectroscopy and Computer-Aided Molecular Design

Published:2000-09-21 Issue:40 Volume:122 Page:9648-9654
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Chen James M.¹,Nelson Frances C.¹,Levin Jeremy I.¹,Mobilio Dominick¹,Moy Franklin J.¹,Nilakantan Ramaswamy¹,Zask Arie¹,Powers Robert¹

Affiliation:

1. Contribution from the Department of Biological Chemistry, Wyeth Research, 85 Bolton St., Cambridge, Massachusetts 02140 and the Department of Chemical Sciences, Wyeth Research, 401 N. Middletown Rd., Pearl River, NY 10965

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja001547g

Reference55 articles.

1. Matrix metalloproteases: Structure-based drug discovery targets

Cited by 115 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Matrix metalloproteases;Metalloenzymes;2024

2. Quinazoline-2-Carboxamides as Selective PET Radiotracers for Matrix Metalloproteinase-13 Imaging in Atherosclerosis;Journal of Medicinal Chemistry;2023-05-09

3. Zebrafish as a model for studying peripheral neuropathy;Handbook of Animal Models in Neurological Disorders;2023

4. The collagenases: are they tractable targets for preventing cartilage destruction in osteoarthritis?;Expert Opinion on Therapeutic Targets;2022-02-01

5. Matrix Metalloproteinase 13 Inhibitors for Modulation of Osteoclastogenesis: Enhancement of Solubility and Stability;ChemMedChem;2021-01-26