3,5-Diaryl-2-aminopyridines as a Novel Class of Orally Active Antimalarials Demonstrating Single Dose Cure in Mice and Clinical Candidate Potential-Reference-Cited by-同舟云学术

3,5-Diaryl-2-aminopyridines as a Novel Class of Orally Active Antimalarials Demonstrating Single Dose Cure in Mice and Clinical Candidate Potential

Published:2012-03-21 Issue:7 Volume:55 Page:3479-3487
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Younis Yassir¹,Douelle Frederic¹,Feng Tzu-Shean¹,Cabrera Diego González¹,Manach Claire Le¹,Nchinda Aloysius T.¹,Duffy Sandra²,White Karen L.³,Shackleford David M.³,Morizzi Julia³,Mannila Janne³,Katneni Kasiram³,Bhamidipati Ravi³,Zabiulla K. Mohammed⁴,Joseph Jayan T.⁴,Bashyam Sridevi⁴,Waterson David⁵,Witty Michael J.⁵,Hardick David⁶,Wittlin Sergio⁷⁸,Avery Vicky²,Charman Susan A.³,Chibale Kelly¹⁹

Affiliation:

1. Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa

2. Discovery Biology, Eskitis Institute, Griffith University (Nathan Campus), Don Young Road, Brisbane, Qld 4111, Australia

3. Centre for Drug Candidate Optimisation, Monash University (Parkville Campus), 381 Royal Parade, Parkville, VIC 3052, Australia

4. Syngene International Ltd., Biocon Park, Plot No. 2 & 3, Bommasandra IV Phase, Jigani Link Road, Bangalore 560099, India

5. Medicines for Malaria Venture, ICC, Route de Pré-Bois 20, P.O. Box 1826, 1215 Geneva, Switzerland

6. BioFocus, Chesterford Research Park, Saffron Walden, Essex CB10 1XL, United Kingdom

7. Swiss Tropical and Public Health Institute, Socinstrasse 57, 4002 Basel, Switzerland

8. University of Basel, Socinstrasse 57, 4002 Basel, Switzerland

9. Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Rondebosch 7701, South Africa

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm3001373

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