Discovery of a Novel Series of CRTH2 (DP2) Receptor Antagonists Devoid of Carboxylic Acids-Reference-Cited by-同舟云学术

Discovery of a Novel Series of CRTH2 (DP2) Receptor Antagonists Devoid of Carboxylic Acids

Published:2011-10-17 Issue:12 Volume:2 Page:938-942
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Crosignani Stefano¹,Jorand-Lebrun Catherine¹,Campbell Gordon¹,Prêtre Adeline¹,Grippi-Vallotton Tania¹,Quattropani Anna¹,Bouscary-Desforges Gwenaelle¹,Bombrun Agnes¹,Missotten Marc¹,Humbert Yves¹,Frémaux Christèle¹,Pâquet Mikaël¹,El Harkani Kamel¹,Bradshaw Charles G.¹,Cleva Christophe¹,Abla Nada¹,Daff Hamina¹,Schott Olivier¹,Pittet Pierre-André¹,Arrighi Jean-François¹,Gaudet Marilène¹,Johnson Zoë¹

Affiliation:

1. Merck Serono S.A., 9 chemin des Mines, CH-1202 Geneva, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ml200223s

Reference19 articles.

1. Antagonism of the prostaglandin D2 receptors DP1 and CRTH2 as an approach to treat allergic diseases

2. Prostaglandin D2 Selectively Induces Chemotaxis in T Helper Type 2 Cells, Eosinophils, and Basophils via Seven-Transmembrane Receptor Crth2

3. Prostaglandin D2-Induced Eosinophilic Airway Inflammation Is Mediated by CRTH2 Receptor