Dual Inhibition of γ-Oryzanol on Cellular Melanogenesis: Inhibition of Tyrosinase Activity and Reduction of Melanogenic Gene Expression by a Protein Kinase A-Dependent Mechanism

Author:

Jun Hee-jin1,Lee Ji Hae1,Cho Bo-Ram1,Seo Woo-Duck2,Kang Hang-Won2,Kim Dong-Woo3,Cho Kang-Jin4,Lee Sung-Joon1

Affiliation:

1. Division of Food Bioscience and Technology, College of Life Sciences and Biotechnology, Korea University, Seoul 136-713, Republic of Korea

2. Department of Functional Crop, National Institute of Crop Science, Miryang 627-803, Republic of Korea

3. Research Center, Natural F & P Corporation, Cheongwon 363-886, Republic of Korea

4. Food Nutrition and Functionality Division, Department of Agrofood Resources, National Academy of Agricultural Science, Suwon, 441-853, Republic of Korea

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

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