Substrate Specificity and Kinetic Studies of PADs 1, 3, and 4 Identify Potent and Selective Inhibitors of Protein Arginine Deiminase 3-Reference-Cited by-同舟云学术

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Substrate Specificity and Kinetic Studies of PADs 1, 3, and 4 Identify Potent and Selective Inhibitors of Protein Arginine Deiminase 3

Published:2010-05-21 Issue:23 Volume:49 Page:4852-4863
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Knuckley Bryan¹,Causey Corey P.¹,Jones Justin E.¹,Bhatia Monica¹,Dreyton Christina J.¹,Osborne Tanesha C.¹,Takahara Hidenari²,Thompson Paul R.¹

Affiliation:

1. Department of Chemistry and Biochemistry, University of South Carolina, 631 Sumter Street, Columbia, South Carolina 29208

2. Department of Applied Bioresource Sciences, School of Agriculture, Ibaraki University, 21-1 Chuou 3, Ami, Inashiki, Ibaraki 3000393, Japan

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi100363t

Reference59 articles.

1. Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies.

2. The Role of Citrullinated Proteins Suggests a Novel Mechanism in the Pathogenesis of Multiple Sclerosis

3. Abnormal accumulation of citrullinated proteins catalyzed by peptidylarginine deiminase in hippocampal extracts from patients with Alzheimer's disease

4. Haplotypes of PADI4 susceptible to rheumatoid arthritis are also associated with ulcerative colitis in the Japanese population

5. Increased PADI4 expression in blood and tissues of patients with malignant tumors

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1. Peptidylarginine deiminase (PAD): A promising target for chronic diseases treatment;International Journal of Biological Macromolecules;2024-10

2. Immobilized PAD4 enzyme on magnetic nanoparticles for screening natural inhibitors from traditional Chinese medicines;Talanta;2024-10

3. G-CSF induces neutrophil extracellular traps formation and promotes ovarian cancer peritoneal dissemination;Journal of Leukocyte Biology;2024-07-31

4. The role of anti-citrullinated protein antibody in pathogenesis of RA;Clinical and Experimental Medicine;2024-07-08

5. naRNA-LL37 composite DAMPs define sterile NETs as self-propagating drivers of inflammation;EMBO Reports;2024-05-23

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