Substrate Specificity and Kinetic Studies of PADs 1, 3, and 4 Identify Potent and Selective Inhibitors of Protein Arginine Deiminase 3

Author:

Knuckley Bryan1,Causey Corey P.1,Jones Justin E.1,Bhatia Monica1,Dreyton Christina J.1,Osborne Tanesha C.1,Takahara Hidenari2,Thompson Paul R.1

Affiliation:

1. Department of Chemistry and Biochemistry, University of South Carolina, 631 Sumter Street, Columbia, South Carolina 29208

2. Department of Applied Bioresource Sciences, School of Agriculture, Ibaraki University, 21-1 Chuou 3, Ami, Inashiki, Ibaraki 3000393, Japan

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

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3. Small molecule activates citrullination through targeting PAD2;Philosophical Transactions of the Royal Society B: Biological Sciences;2023-10-02

4. Protein citrullination: inhibition, identification and insertion;Philosophical Transactions of the Royal Society B: Biological Sciences;2023-10-02

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