Effects on Molecular Conformation and Anticoagulant Activities of 1,6-Anhydrosugars at the Reducing Terminal of Antithrombin-Binding Octasaccharides Isolated from Low-Molecular-Weight Heparin Enoxaparin-Reference-Cited by-同舟云学术

Effects on Molecular Conformation and Anticoagulant Activities of 1,6-Anhydrosugars at the Reducing Terminal of Antithrombin-Binding Octasaccharides Isolated from Low-Molecular-Weight Heparin Enoxaparin

Published:2010-10-28 Issue:22 Volume:53 Page:8030-8040
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Guerrini Marco¹,Elli Stefano¹,Gaudesi Davide¹,Torri Giangiacomo¹,Casu Benito¹,Mourier Pierre²,Herman Frederic²,Boudier Christian³,Lorenz Martin²,Viskov Christian²

Affiliation:

1. “G. Ronzoni” Institute for Chemical and Biochemical Research, via G. Colombo 81, 20133 Milan, Italy

2. Sanofi-Aventis, 13 Quai Jules Guesde, 94403 Vitry sur Seine, France

3. CNRS UMR 7175, Département Physicochimie et Pharmacochimie des Interactions Moléculaires et Cellulaires, Faculté de Pharmacie, Université Louis Pasteur, Strasbourg I, F 67401, France

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm100771s

Reference38 articles.

1. Heparin and low-molecular-weight heparin

2. 2003 Claude S. Hudson Award Address in Carbohydrate Chemistry. Heparin: Structure and Activity

3. Heparin and Low Molecular Weight Heparin in Thrombosis and Inflammation

4. Structure and biological interactions of heparin and heparan sulfate

5. Structural variation in the antithrombin III binding site region and its occurrence in heparin from different sources

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