Pharmacometabonomic Characterization of Xenobiotic and Endogenous Metabolic Phenotypes That Account for Inter-individual Variation in Isoniazid-Induced Toxicological Response-Reference-Cited by-同舟云学术

Pharmacometabonomic Characterization of Xenobiotic and Endogenous Metabolic Phenotypes That Account for Inter-individual Variation in Isoniazid-Induced Toxicological Response

Published:2012-08-09 Issue:9 Volume:11 Page:4630-4642
ISSN:1535-3893
Container-title:Journal of Proteome Research
language:en
Short-container-title:J. Proteome Res.

Author:

Cunningham Katharine¹,Claus Sandrine P.²,Lindon John C.¹,Holmes Elaine¹,Everett Jeremy R.³,Nicholson Jeremy K.¹,Coen Muireann¹

Affiliation:

1. Biomolecular Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, South Kensington, London SW7 2AZ, U.K.

2. Department of Food and Nutritional Sciences, The University of Reading, Whiteknights, PO Box 226, Reading RG6 6AP, U.K.

3. Pharmaceutical, Chemical and Environmental Sciences, School of Science, University of Greenwich at Medway, Central Avenue, Chatham Maritime, Kent ME4 4TB, U.K.

Publisher

American Chemical Society (ACS)

Subject

General Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/pr300430u

Reference64 articles.

1. Isoniazid: Metabolic Aspects and Toxicological Correlates

2. Isoniazid and Iproniazid: Activation of Metabolites to Toxic Intermediates in Man and Rat

3. The Role of Metabolism in the Hepatotoxicity of Isoniazid and Iproniazid

4. Isoniazid Liver Injury: Clinical Spectrum, Pathology, and Probable Pathogenesis

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