Discrimination of Ligands with Different Flexibilities Resulting from the Plasticity of the Binding Site in Tubulin-Reference-Cited by-同舟云学术

Discrimination of Ligands with Different Flexibilities Resulting from the Plasticity of the Binding Site in Tubulin

Published:2012-08-27 Issue:36 Volume:51 Page:7138-7148
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Chakraborti Soumyananda¹,Chakravarty Devlina¹,Gupta Suvroma²,Chatterji Biswa Prasun³,Dhar Gopa¹,Poddar Asim¹,Panda Dulal³,Chakrabarti Pinak¹⁴,Ghosh Dastidar Shubhra⁴,Bhattacharyya Bhabatarak¹

Affiliation:

1. Department of Biochemistry, Bose Institute, Kolkata 700054, India

2. Department of Biotechnology, Haldia Institute of Technology, ICARE Complex, Purba Medinipur 721657, India

3. Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai 400076, India

4. Bioinformatics Centre, Bose Institute, Kolkata 700054, India

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi300474q

Reference49 articles.

1. Microtubules as a target for anticancer drugs

2. Microtubule assembly dynamics: An attractive target for anticancer drugs

3. Peloruside- and Laulimalide-Resistant Human Ovarian Carcinoma Cells Have βI-Tubulin Mutations and Altered Expression of βII- and βIII-Tubulin Isotypes

4. Mutations in the β-tubulin binding site for peloruside A confer resistance by targeting a cleft significant in side chain binding

5. Mechanisms of Taxol resistance related to microtubules

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