Metabolism and Toxicity of Thioacetamide and Thioacetamide S-Oxide in Rat Hepatocytes-Reference-Cited by-同舟云学术

Metabolism and Toxicity of Thioacetamide and Thioacetamide S-Oxide in Rat Hepatocytes

Published:2012-08-17 Issue:9 Volume:25 Page:1955-1963
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Hajovsky Heather¹,Hu Gang¹,Koen Yakov¹,Sarma Diganta¹,Cui Wenqi¹,Moore David S.¹,Staudinger Jeff L.¹,Hanzlik Robert P.¹

Affiliation:

1. Department of Medicinal Chemistry, ‡Department of Pharmacology & Toxicology, and §Microscopy & Analytical Imaging Laboratory, The University of Kansas, Lawrence, Kansas 66045, United States

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx3002719

Reference36 articles.

1. Liver Tumors in Rats Fed Thiourea or Thioacetamide

2. Thioacetamide-induced intestinal-type cholangiocarcinoma in rat: an animal model recapitulating the multi-stage progression of human cholangiocarcinoma

3. Reproducible production of thioacetamide-induced macronodular cirrhosis in the rat with no mortality

4. Overexpression of thioredoxin prevents thioacetamide-induced hepatic fibrosis in mice

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