Novel Pyridazinone Inhibitors for Vascular Adhesion Protein-1 (VAP-1): Old Target–New Inhibition Mode-Reference-Cited by-同舟云学术

Novel Pyridazinone Inhibitors for Vascular Adhesion Protein-1 (VAP-1): Old Target–New Inhibition Mode

Published:2013-12-13 Issue:24 Volume:56 Page:9837-9848
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bligt-Lindén Eva¹,Pihlavisto Marjo²,Szatmári István³,Otwinowski Zbyszek⁴,Smith David J.²,Lázár László³,Fülöp Ferenc³,Salminen Tiina A.¹

Affiliation:

1. Structural Bioinformatics Laboratory, Department of Biosciences, Åbo Akademi University, FI-20520 Turku, Finland

2. Biotie Therapies Corporation, FI-20520 Turku, Finland

3. Institute of Pharmaceutical Chemistry and Stereochemistry Research Group of Hungarian Academy of Sciences, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary

4. Otwinowski Laboratory, Department of Biophysics and Department of Biochemistry, UT Southwestern Medical Center, Dallas, Texas 75390-8816, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm401372d

Reference59 articles.

1. Floris, G.Copper Amine Oxidases: Structures, Catalytic Mechanisms, And Role in Pathophysiology;CRC Press:Boca Raton, FL, 2009; p344.

2. Cloning of Vascular Adhesion Protein 1 Reveals a Novel Multifunctional Adhesion Molecule

3. VAP-1: an adhesin and an enzyme

4. Ectoenzymes controlling leukocyte traffic

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