Telescoped Approach to Aryl Hydroxymethylation in the Synthesis of a Key Pharmaceutical Intermediate-Reference-Cited by-同舟云学术

Telescoped Approach to Aryl Hydroxymethylation in the Synthesis of a Key Pharmaceutical Intermediate

Published:2013-06-06 Issue:12 Volume:78 Page:5955-5963
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Slattery Catherine N.¹,Deasy Rebecca E.¹,Maguire Anita R.¹,Kopach Michael E.²,Singh Utpal K.²,Argentine Mark D.²,Trankle William G.²,Scherer Roger Brian²,Moynihan Humphrey³

Affiliation:

1. Department of Chemistry and School of Pharmacy, Analytical and Biological Chemistry Research Facility, University College Cork, Cork, Ireland

2. Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, United States

3. Eli Lilly SA, Dunderrow, Kinsale, Cork, Ireland

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo400647t

Reference21 articles.

1. Eli Lilly and Company. Treatment of Pervasive Developmental Disorders with NorepinephrineReuptake Inhibitors, WO2005/20975 A2, 2005.

2. aSchwarz Pharma, Ltd. ShortenedSynthesis Using Paraformaldehyde or Trioxanes, US8,115,028, 2012.

3. bMiteni, S. P. A.,Process for the Preparation of 3,5-bis(trifluoromethyl) benzylalcohol, WO2005/035472A1, 2005.

4. aHoffman LaRoche, Inc. Chloromethylation of BenzeneCompounds, US3,465,051, 1969.

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