Paclitaxel-Conjugated PAMAM Dendrimers Adversely Affect Microtubule Structure through Two Independent Modes of Action

Author:

Cline Erika N.1,Li Ming-Hsin1,Choi Seok Ki1,Herbstman Jeffrey F.1,Kaul Neha1,Meyhöfer Edgar1,Skiniotis Georgios1,Baker James R.1,Larson Ronald G.1,Walter Nils G.1

Affiliation:

1. Cellular and Molecular Biology Graduate Program,‡Single Molecule Analysis Group, §Department of Biomedical Engineering, ∥Michigan Nanotechnology Institute for Medicine and Biological Sciences, ⊥Department of Internal Medicine, #Life Sciences Institute, ○Department of Mechanical Engineering, □Department of Chemical Engineering, and ΔDepartment of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, United States

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,Polymers and Plastics,Biomaterials,Bioengineering

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