Discovery of Small Molecule Vanin Inhibitors: New Tools To Study Metabolism and Disease-Reference-Cited by-同舟云学术

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Discovery of Small Molecule Vanin Inhibitors: New Tools To Study Metabolism and Disease

Published:2013-01-02 Issue:3 Volume:8 Page:530-534
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Jansen Patrick A. M.,van Diepen Janna A.,Ritzen Bas¹,Zeeuwen Patrick L. J. M.,Cacciatore Ivana²,Cornacchia Catia²,van Vlijmen-Willems Ivonne M. J. J.,de Heuvel Erik³,Botman Peter N. M.³,Blaauw Richard H.³,Hermkens Pedro H. H.¹,Rutjes Floris P. J. T.¹,Schalkwijk Joost

Affiliation:

1. Department of Synthetic Organic Chemistry, Institute for Molecules and Materials, Radboud University Nijmegen, The Netherlands

2. Department of Pharmacy, “G. d’Annunzio” University, Chieti-Pescara, Italy

3. Chiralix B.V., Nijmegen, The Netherlands

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/cb3006424

Reference26 articles.

1. Is pantetheinase the actual identity of mouse and human vanin-1 proteins?

2. Diverse biological activities of the vascular non-inflammatory molecules – The Vanin pantetheinases

3. Vanin genes are clustered (human 6q22-24 and mouse 10A2B1) and encode isoforms of pantetheinase ectoenzymes

4. Pantetheinase activity of membrane-bound Vanin-1: lack of free cysteamine in tissues of Vanin-1 deficient mice

5. Catalysis in the nitrilase superfamily

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1. A highly specific two-photon fluorescent probe for pantetheinase and its biological applications;Sensors and Actuators B: Chemical;2024-06

2. Patent Highlights June–July 2023;Pharmaceutical Patent Analyst;2024-04-26

3. Vanin1 (VNN1) in chronic diseases: Future directions for targeted therapy;European Journal of Pharmacology;2024-01

4. Serum levels of Vanin-2 increase with obesity in relation to inflammation of adipose tissue and may be a predictor of bariatric surgery outcomes;Frontiers in Nutrition;2023-12-14

5. Vanin-1-Activated Chemiluminescent Probe: Help to Early Diagnosis of Acute Kidney Injury with High Signal-to-Noise Ratio through Urinalysis;Analytical Chemistry;2023-09-21

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