Synthesis, Antimalarial Activity, Biomimetic Iron(II) Chemistry, and in Vivo Metabolism of Novel, Potent C-10-Phenoxy Derivatives of Dihydroartemisinin-Reference-Cited by-同舟云学术

Synthesis, Antimalarial Activity, Biomimetic Iron(II) Chemistry, and in Vivo Metabolism of Novel, Potent C-10-Phenoxy Derivatives of Dihydroartemisinin

Published:2000-11-23 Issue:1 Volume:44 Page:58-68
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

O'Neill Paul M.¹,Miller Alison¹,Bishop Laurence P. D.¹,Hindley Stephen¹,Maggs James L.¹,Ward Stephen A.¹,Roberts Stanley M.¹,Scheinmann Feodor¹,Stachulski Andrew V.¹,Posner Gary H.¹,Park B. Kevin¹

Affiliation:

1. Robert Robinson Laboratories, University of Liverpool, Liverpool L69 7ZD, England, Department of Pharmacology and Therapeutics, University of Liverpool, Liverpool L69 3GE, England, UFC Ltd., Synergy House, Guildhall Close, Manchester Science Park, Manchester M15 6SY, England, and Department of Chemistry, The Johns Hopkins University, Remsen Hall, Baltimore, Maryland 21218

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm000987f

Reference46 articles.

1. Quinoline antimalarials: Mechanisms of action and resistance

2. The toxicity of artemisinin and related compounds on neuronal and glial cells in culture

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