Quantitative LC–MS/MS. 1. Impact of Points across a Peak on the Accuracy and Precision of Peak Area Measurements

Author:

Zeng Wei1,Bateman Kevin P.1ORCID

Affiliation:

1. Preclinical Development, MRL, Merck & Co., Inc., West Point, Pennsylvania 19486-0004, United States

Publisher

American Chemical Society (ACS)

Subject

Spectroscopy,Structural Biology

Reference22 articles.

1. M10 Bioanalytical Method Validation and Study Sample Analysis. U.S. Food And Drug Administration. 2022, November 7 ed.; FDA: https://www.fda.gov/regulatory-information/search-fda-guidance-documents/m10-bioanalytical-method-validation-and-study-sample-analysis, 2022.

2. Standardized workflows for increasing efficiency and productivity in discovery stage bioanalysis

3. Fundamentals of tandem mass spectrometry: a dynamics study of simple C−C bond cleavage in collision-activated dissociation of polyatomic ions at low energy

4. The ideal mass analyzer: Fact or fiction?

5. Peak distortion, data sampling errors and the integrator in the measurement of very narrow chromatographic peaks

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