Rapid Intact Mass Analysis and Evaluation of the Separation Potential of Microfluidic Capillary Electrophoresis Mass Spectrometry for Oligonucleotides

Author:

Lippens Jennifer L.1ORCID,Timmons Heath C.1,Welch Crystal2,Kulkarni Aditya2,Flick Tawnya G.1

Affiliation:

1. Pivotal Attribute Sciences, Amgen, Thousand Oaks, California 91320, United States

2. 908 Devices, Boston, Massachusetts 94720-1460, United States

Publisher

American Chemical Society (ACS)

Subject

Spectroscopy,Structural Biology

Reference37 articles.

1. Oligonucleotide Therapeutics — A New Class of Cholesterol-Lowering Drugs

2. Oligonucleotide therapeutics in neurodegenerative diseases

3. mRNA medicines we are currently developing. Moderna. https://www.modernatx.com/en-US/research/product-pipeline? (accessed 2022–08–02).

4. Product Pipeline: Pharmaceutical Pipeline for New Drugs | Pfizer. https://www.pfizer.com/science/drug-product-pipeline (accessed 2022–08–02).

5. Amgen Pipeline. https://www.amgenpipeline.com (accessed 2022–08–02).

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