New Opioid Designed Multiple Ligand from Dmt-Tic and Morphinan Pharmacophores-Reference-Cited by-同舟云学术

New Opioid Designed Multiple Ligand from Dmt-Tic and Morphinan Pharmacophores

Published:2006-07-27 Issue:18 Volume:49 Page:5640-5643
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Neumeyer John L.¹,Peng Xuemei¹,Knapp Brian I.¹,Bidlack Jean M.¹,Lazarus Lawrence H.¹,Salvadori Severo¹,Trapella Claudio¹,Balboni Gianfranco¹

Affiliation:

1. Alcohol and Drug Abuse Research Center, McLean Hospital, Harvard Medical School, 115 Mill Street, Belmont, Massachusetts 02478, Department of Pharmacology and Physiology, School of Medicine and Dentistry, University of Rochester, Rochester, New York 14642, Medicinal Chemistry Group, Laboratory of Pharmacology and Chemistry, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, Department of Pharmaceutical Sciences and Biotechnology Center, University of...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0605785

Reference20 articles.

1. Can we rationally design promiscuous drugs?

2. Designed Multiple Ligands. An Emerging Drug Discovery Paradigm

3. From magic bullets to designed multiple ligands

4. A chimeric opioid peptide with mixed μ agonist/δ antagonist properties

5. Synthesis and Preliminary In vitro Investigation of Bivalent Ligands Containing Homo- and Heterodimeric Pharmacophores at μ, δ, and κ Opioid Receptors

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