Structure−Activity Relationship Study and Drug Profile of N-(4-Fluorophenylsulfonyl)-l-valyl-l-leucinal (SJA6017) as a Potent Calpain Inhibitor-Reference-Cited by-同舟云学术

Structure−Activity Relationship Study and Drug Profile of N-(4-Fluorophenylsulfonyl)-l-valyl-l-leucinal (SJA6017) as a Potent Calpain Inhibitor

Published:2003-02-01 Issue:5 Volume:46 Page:868-871
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Inoue Jun¹,Nakamura Masayuki¹,Cui Ying-She¹,Sakai Yusuke¹,Sakai Osamu¹,Hill Jeanette R.¹,Wang Kevin K. W.¹,Yuen Po-Wai¹

Affiliation:

1. Kobe Creative Center, Senju Pharmaceutical Co., LTD, 1-5-4 Murotani, Nishi-ku, Kobe, Hyogo 651-2241, Japan, Ricerca, LLC, 7528 Auburn Road PO Box 1000 Concord, Ohio 44077, and Neuroscience Therapeutics, Pfizer Global Research and Development, Ann Arbor Laboratories, 2800 Plymouth Road, Ann Arbor, Michigan 48105

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0201924

Reference25 articles.

1. New era of calpain research

2. Calcium-activated neutral protease (calpain) system: structure, function, and regulation.

3. Calpain: new perspectives in molecular diversity and physiological‐pathological involvement

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