Dynamic Modeling of Human 5-Lipoxygenase–Inhibitor Interactions Helps To Discover Novel Inhibitors-Reference-Cited by-同舟云学术

Dynamic Modeling of Human 5-Lipoxygenase–Inhibitor Interactions Helps To Discover Novel Inhibitors

Published:2012-03-01 Issue:6 Volume:55 Page:2597-2605
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wu Yiran¹,He Chong¹,Gao Yang¹,He Shan¹,Liu Ying¹,Lai Luhua¹

Affiliation:

1. BNLMS, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, College of Chemistry and Molecular Engineering, ‡Center for Theoretical Biology, and §Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm201497k

Reference61 articles.

1. Arachidonate 5-lipoxygenase

2. Regulation of the activity of 5-lipoxygenase, a key enzyme in leukotriene biosynthesis

3. The Role of Leukotrienes in Inflammation

4. Pharmacological intervention with 5-lipoxygenase: new insights and novel compounds

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