Synthesis of Amphotericin B. A Convergent Strategy to the Polyol Segment of the Heptaene Macrolide Antibiotics-Reference-Cited by-同舟云学术

Synthesis of Amphotericin B. A Convergent Strategy to the Polyol Segment of the Heptaene Macrolide Antibiotics

Published:1996-01-01 Issue:17 Volume:61 Page:5704-5705
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

McGarvey Glenn J.¹,Mathys Jeffrey A.¹,Wilson Kenneth J.¹

Affiliation:

1. Department of Chemistry, University of Virginia, Charlottesville, Virginia 22901

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo9609337

Reference15 articles.

1. Omura, S.; Tanaka, H. InMacrolide Antibiotics: Chemistry, Biology, and Practice; Omura, S., Ed.; Academic Press: New York, 1984; pp 351−404. We refer to those structures that differ from a heptaene macrolide antibiotic (e.g.1) by saturation at C28−C29 as pseudoheptaene macrolide antibiotics (e.g.2).

2. Amphotericin B: 30 Years of Clinical Experience

3. For a review: Beau, J.M. InRecent Progress in the Chemical Synthesis of Antibiotics; Lukacs, G., Ohno, M., Eds.; Springer-Verlag: Berlin, 1990; pp 135−182.

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