Cyclostreptin (FR182877), an Antitumor Tubulin-Polymerizing Agent Deficient in Enhancing Tubulin Assembly Despite Its High Affinity for the Taxoid Site

Author:

Edler Michael C.1,Buey Rubén M.1,Gussio Rick1,Marcus Adam I.1,Vanderwal Christopher D.1,Sorensen Erik J.1,Díaz J. Fernando1,Giannakakou Paraskevi1,Hamel Ernest1

Affiliation:

1. Screening Technologies Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute at Frederick, National Institutes of Health, Frederick, Maryland 21702, Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Cientificas, 28040 Madrid, Spain, Information Technology Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute at Frederick, National Institutes of Health, Frederick,...

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Reference48 articles.

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