Structure−Activity Studies and Analgesic Efficacy of N-(3-Pyridinyl)-Bridged Bicyclic Diamines, Exceptionally Potent Agonists at Nicotinic Acetylcholine Receptors-Reference-Cited by-同舟云学术

Structure−Activity Studies and Analgesic Efficacy of N-(3-Pyridinyl)-Bridged Bicyclic Diamines, Exceptionally Potent Agonists at Nicotinic Acetylcholine Receptors

Published:2007-06-22 Issue:15 Volume:50 Page:3627-3644
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bunnelle William H.¹,Daanen Jerome F.¹,Ryther Keith B.¹,Schrimpf Michael R.¹,Dart Michael J.¹,Gelain Arianna¹,Meyer Michael D.¹,Frost Jennifer M.¹,Anderson David J.¹,Buckley Michael¹,Curzon Peter¹,Cao Ying-Jun¹,Puttfarcken Pamela¹,Searle Xenia¹,Ji Jianguo¹,Putman C. Brent¹,Surowy Carol¹,Toma Lucio¹,Barlocco Daniela¹

Affiliation:

1. Neuroscience Research, Abbott Laboratories, Department R47W, Building AP9A, Abbott Park, Illinois 60064-6117, Istituto di Chimica Farmaceutica e Tossicologica, Università di Milano, Viale Abruzzi 42, 20131 Milano, Italy, and Dipartimento di Chimica Organica, Università di Pavia, via Taramelli 10, 27100 Pavia, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm070018l

Reference70 articles.

1. Nicotinic treatment of Alzheimer’s disease

2. Acute effects of the selective cholinergic channel activator (nicotinic agonist) ABT-418 in Alzheimer's disease

3. Schizophrenia, Sensory Gating, and Nicotinic Receptors

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