Scaffold Explorer: An Interactive Tool for Organizing and Mining Structure−Activity Data Spanning Multiple Chemotypes
Author:
Affiliation:
1. Johnson & Johnson Pharmaceutical Research & Development, LLC, Welsh & McKean Roads, Spring House, Pennsylvania 19477
2. Johnson & Johnson Pharmaceutical Research & Development, LLC, 3210 Merryfield Road, San Diego, California 92121
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm1004495
Reference39 articles.
1. Scaffold hopping
2. On Combining Recursive Partitioning and Simulated Annealing To Detect Groups of Biologically Active Compounds
3. Learning from the Data: Mining of Large High-Throughput Screening Databases
4. Structural Unit Analysis Identifies Lead Series and Facilitates Scaffold Hopping in Combinatorial Chemistry
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