Discovery of 3-[(4,5,7-Trifluorobenzothiazol-2-yl)methyl]indole-N-acetic Acid (Lidorestat) and Congeners as Highly Potent and Selective Inhibitors of Aldose Reductase for Treatment of Chronic Diabetic Complications-Reference-Cited by-同舟云学术

Discovery of 3-[(4,5,7-Trifluorobenzothiazol-2-yl)methyl]indole-N-acetic Acid (Lidorestat) and Congeners as Highly Potent and Selective Inhibitors of Aldose Reductase for Treatment of Chronic Diabetic Complications

Published:2005-03-30 Issue:9 Volume:48 Page:3141-3152
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Van Zandt Michael C.¹,Jones Michael L.¹,Gunn David E.¹,Geraci Leo S.¹,Jones J. Howard¹,Sawicki Diane R.¹,Sredy Janet¹,Jacot Jorge L.¹,DiCioccio A. Thomas¹,Petrova Tatiana¹,Mitschler Andre¹,Podjarny Alberto D.¹

Affiliation:

1. The Institute for Diabetes Discovery, LLC, 23 Business Park Drive, Branford, Connecticut 06405, and Departement de Biologie et Genomique Structurales, UMR 7104 du CNRS, IGBMC, 1 rue Laurent Fries, B.P. 163, 67404 Illkirch Cedex, France

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0492094

Reference65 articles.

1. Hyperglycemic Pseudohypoxia and Diabetic Complications

2. Biochemical Pathways for Microvascular Complications of Diabetes Mellitus

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