Univalent and Bivalent Ligands of Butorphan: Characteristics of the Linking Chain Determine the Affinity and Potency of Such Opioid Ligands-Reference-Cited by-同舟云学术

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Univalent and Bivalent Ligands of Butorphan: Characteristics of the Linking Chain Determine the Affinity and Potency of Such Opioid Ligands

Published:2009-07-27 Issue:23 Volume:52 Page:7389-7396
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Decker Michael¹,Fulton Brian S.¹,Zhang Bin¹,Knapp Brian I.²,Bidlack Jean M.²,Neumeyer John L.¹

Affiliation:

1. Alcohol & Drug Abuse Research Center, McLean Hospital, Harvard Medical School, 115 Mill Street, Belmont, Massachusetts 02478-9106

2. Department of Pharmacology and Physiology, School of Medicine and Dentistry, University of Rochester, Rochester, New York 14642

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm900379p

Reference21 articles.

1. Design and Synthesis of Novel Dimeric Morphinan Ligands for κ and μ Opioid Receptors

2. Synthesis and Preliminary In vitro Investigation of Bivalent Ligands Containing Homo- and Heterodimeric Pharmacophores at μ, δ, and κ Opioid Receptors

3. Kappa Receptor Bivalent Ligands

4. Some Observations Concerning Steric Factors

5. Aminolysis of esters. I. Kinetics and mechanism in anhydrous dioxane

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