Active Site Pressurization: A New Tool for Structure-Guided Drug Design and Other Studies of Protein Flexibility
Author:
Affiliation:
1. School of Pharmacy and Centre for Biomolecular Sciences, University of Nottingham, Nottingham NG7 2RD, U.K.
Publisher
American Chemical Society (ACS)
Subject
Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ci7004725
Reference25 articles.
1. Protein-ligand docking: Current status and future challenges
2. Incorporating Protein Flexibility in Structure-Based Drug Discovery: Using HIV-1 Protease as a Test Case
3. Automated docking to multiple target structures: Incorporation of protein mobility and structural water heterogeneity in AutoDock
4. Modelling protein unfolding: a solvent insertion protocol
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