Binding Site Elucidation of Hydantoin-Based Antagonists of LFA-1 Using Multidisciplinary Technologies: Evidence for the Allosteric Inhibition of a Protein−Protein Interaction-Reference-Cited by-同舟云学术

Binding Site Elucidation of Hydantoin-Based Antagonists of LFA-1 Using Multidisciplinary Technologies: Evidence for the Allosteric Inhibition of a Protein−Protein Interaction

Published:2001-05-26 Issue:24 Volume:123 Page:5643-5650
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Last-Barney Kathleen¹,Davidson Walter¹,Cardozo Mario¹,Frye Leah L.¹,Grygon Christine A.¹,Hopkins Jerry L.¹,Jeanfavre Deborah D.¹,Pav Susan¹,Qian Chungeng¹,Stevenson James M.¹,Tong Liang¹,Zindell Renee¹,Kelly Terence A.¹

Affiliation:

1. Contribution from the Research and Development Center, Boehringer Ingelheim Pharmaceuticals, 900 Ridgebury Road, P.O. Box 368, Ridgefield, Connecticut 06877

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja0104249

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2. Leukocyte adhesion: CD11/CD18 integrins and intercellular adhesion molecules

3. Cloning and characterization of a new intercellular adhesion molecule ICAM-R

4. LEUKOCYTE ADHESION DEFICIENCY: An Inherited Defect in the Mac-1, LFA-1, and p150,95 Glycoproteins

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