Discovery of 4-Benzoyl-1-[(4-methoxy-1H- pyrrolo[2,3-b]pyridin-3-yl)oxoacetyl]-2- (R)-methylpiperazine (BMS-378806): A Novel HIV-1 Attachment Inhibitor That Interferes with CD4-gp120 Interactions-Reference-Cited by-同舟云学术

Discovery of 4-Benzoyl-1-[(4-methoxy-1H- pyrrolo[2,3-b]pyridin-3-yl)oxoacetyl]-2- (R)-methylpiperazine (BMS-378806): A Novel HIV-1 Attachment Inhibitor That Interferes with CD4-gp120 Interactions

Published:2003-08-30 Issue:20 Volume:46 Page:4236-4239
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wang Tao¹,Zhang Zhongxing¹,Wallace Owen B.¹,Deshpande Milind¹,Fang Haiquan¹,Yang Zheng¹,Zadjura Lisa M.¹,Tweedie Donald L.¹,Huang Stella¹,Zhao Fang¹,Ranadive Sunanda¹,Robinson Brett S.¹,Gong Yi-Fei¹,Ricarrdi Keith¹,Spicer Timothy P.¹,Deminie Carol¹,Rose Ronald¹,Wang Hwei-Gene Heidi¹,Blair Wade S.¹,Shi Pei-Yong¹,Lin Pin-fang¹,Colonno Richard J.¹,Meanwell Nicholas A.¹

Affiliation:

1. Department of Discovery Chemistry, Department of Lead Discovery, Department of Virology, Department of Analytical Sciences, Department of Metabolism and Pharmacokinetics, The Bristol-Myers Squibb Pharmaceutical Research Institute, Wallingford, Connecticut 06492 and Department of Pharmaceutics, The Bristol-Myers Squibb Pharmaceutical Research Institute, New Brunswick, New Jersey 08903

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm034082o

Reference23 articles.

1. HIV chemotherapy

2. Structured Treatment Interruption in Patients Infected with HIV

3. Antiretroviral-Drug Resistance among Patients Recently Infected with HIV

4. New antiretroviral agents: looking beyond protease and reverse transcriptase

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