Refinement and Evaluation of a Pharmacophore Model for Flavone Derivatives Binding to the Benzodiazepine Site of the GABAA Receptor-Reference-Cited by-同舟云学术

Refinement and Evaluation of a Pharmacophore Model for Flavone Derivatives Binding to the Benzodiazepine Site of the GABAA Receptor

Published:2002-08-09 Issue:19 Volume:45 Page:4188-4201
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kahnberg Pia¹,Lager Erik¹,Rosenberg Celia¹,Schougaard Jette¹,Camet Linda¹,Sterner Olov¹,Nielsen Elsebet Østergaard¹,Nielsen Mogens¹,Liljefors Tommy¹

Affiliation:

1. Department of Organic and Bioorganic Chemistry, Lund University, P.O. Box 124, S-221 00 Lund, Sweden, Department of Medicinal Chemistry, Royal Danish School of Pharmacy, Universitetsparken 2, DK-2100 Copenhagen, Denmark, and NeuroSearch A/S, Ballerup, Denmark

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm020839k

Reference42 articles.

1. Localizing 3H-GABA in Nerve Terminals of Rat Cerebral Cortex by Electron Microscopic Autoradiography

2. Distribution of GABAA and GABAB receptors in mammalian brain: Potential targets for drug development

3. GABAA receptors: immunocytochemical distribution of 13 subunits in the adult rat brain

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