Synthesis of Sominone and Its Derivatives Based on an RCM Strategy: Discovery of A Novel Anti-Alzheimer’s Disease Medicine Candidate “Denosomin”-Reference-Cited by-同舟云学术

Synthesis of Sominone and Its Derivatives Based on an RCM Strategy: Discovery of A Novel Anti-Alzheimer’s Disease Medicine Candidate “Denosomin”

Published:2009-08-04 Issue:17 Volume:11 Page:3970-3973
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Matsuya Yuji¹,Yamakawa Yu-ichiro¹,Tohda Chihiro¹,Teshigawara Kiyoshi¹,Yamada Masashi¹,Nemoto Hideo¹

Affiliation:

1. Graduate School of Medicine and Pharmaceutical Sciences and Institute of Natural Medicine, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan, and Research Alliance & Portfolio Strategy, Taiho Pharmaceutical Co. Ltd., 1-2-4 Utikanda, Chiyoda-ku, Tokyo 101-0047, Japan

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ol901553w

Reference29 articles.

1. Dendrite extension by methanol extract of Ashwagandha (roots of Withania somnifera) in SK-N-SH cells

2. Withanolide Derivatives from the Roots of Withania somnifera and Their Neurite Outgrowth Activities.

3. Axon- or dendrite-predominant outgrowth induced by constituents from Ashwagandha

4. Neuritic regeneration and synaptic reconstruction induced by withanolide A

5. Withanoside IV and its active metabolite, sominone, attenuate Aβ(25-35)-induced neurodegeneration

Cited by 37 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Divergent synthesis of complex withanolides enabled by a scalable route and late-stage functionalization;Science Advances;2024-06-28

2. Total Synthesis of the Diterpenes (+)-Randainin D and (+)-Barekoxide via Photoredox-Catalyzed Deoxygenative Allylation;Journal of the American Chemical Society;2024-04-15

3. Total Synthesis and Structure Revision of (+)-Lancilactone C;Journal of the American Chemical Society;2023-06-16

4. Synthesis and Cytotoxicity Evaluation of Betulin Cycloolefin Derivatives by Ruthenium-Catalyzed Ring-Closing Metathesis;Journal of Natural Products;2023-03-01

5. Natural Medicines and Their Underlying Mechanisms of Prevention and Recovery from Amyloid Β-Induced Axonal Degeneration in Alzheimer’s Disease;International Journal of Molecular Sciences;2020-06-30