(Z,Z)-2,7-Bis(4-amidinobenzylidene)cycloheptan-1-one: Identification of a Highly Active Inhibitor of Blood Coagulation Factor Xa
Author:
Affiliation:
1. Discovery Research, Berlex Biosciences, 15049 San Pablo Avenue, P.O. Box 4099, Richmond, California 94804-0099
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm980281%2B
Reference47 articles.
1. Activation-dependent Exposure of the Inter-EGF Sequence Leu83-Leu88 in Factor Xa Mediates Ligand Binding to Effector Cell Protease Receptor-1
2. Effector Cell Protease Receptor-1, a Platelet Activation-dependent Membrane Protein, Regulates Prothrombinase-catalyzed Thrombin Generation
3. Importance of factor Xa in determining the procoagulant activity of whole-blood clots.
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1. Green, rapid, and highly efficient syntheses of α , α′ ‐bis[(aryl or allyl)idene]cycloalkanones and 2‐[(aryl or allyl)idene]‐1‐indanones as potentially biologic compounds via solvent‐free microwave‐assisted Claisen–Schmidt condensation catalyzed by MoCl 5;Journal of the Chinese Chemical Society;2019-08-23
2. Developments in factor Xa inhibitors for the treatment of thromboembolic disorders;Medicinal Research Reviews;2011-02-03
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5. Bisbenzylidene cycloalkanone: a versatile molecule as a polymer building block;Journal of Materials Chemistry;2010
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