1. Department of Biology, Centre for Research in Mass Spectrometry, and Department of Chemistry, York University, 4700 Keele Street, Toronto, Ontario, Canada M3J 1P3, Division of Clinical Biochemistry, St. Michael's Hospital, 30 Bond Street, Toronto, Ontario, Canada M5B 1W8, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada M5G 1L5, and Pathology and Laboratory Medicine, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, Canada M5G 1X5