Type-2 Diabetes Mellitus of Degenerative Disease

Abstract

Diabetes mellitus as a degenerative disease is difficult to cure but can be prevented by knowing the symptoms from the beginning. Developmental stage of diabetes: normal, prediabetes and diabetes. Diabetes mellitus can be divided into type-1 diabetes mellitus, type 2 diabetes mellitus, gestational diabetes mellitus and other types of diabetes mellitus. People with diabetes melitus type-2 90% of all diabetics. Type 2 diabetes mellitus is inherited polygenically. The genes that cause type 2 diabetes melitus include TCF7L2 gene, KCNJ11, HHEX, SLC30A8, CDKAL1, CDKN2A / 2B, IGF2BP2, and KCNQ, PPARG CAPN10, MC4R and FTO Genes. Type 2 diabetes mellitus risk factors: family history of diabetes mellitus, obesity, smokers, hypertension, history of coronary heart disease, lack of rest, and stress.Key words: DM, TCF7L2 and SNP