Normal-Tension Glaucoma: Epidemiology, Pathogenesis, Diagnosis and Treatment. Literature Review. Part 2. Role of Vascular Dysregulation in the Pathogenesis. Treatment of Normal Tension Glaucoma

Author:

Kurysheva N. I.1ORCID,Kim V. E.2ORCID,Plieva H. M.2ORCID,Kim V. Yu.2ORCID

Affiliation:

1. Medical Biological University of Innovations and Continuing Education of the Federal State Budgetary University the State Research Center — Burnasyan Federal Medical Biophysical Center; Ophthalmological Center of the Federal Medical and Biological Agency of the Russian Federation — Burnasyan Federal Medical Biophysical Center; Postgraduate Education Academy of the Burnasyan Federal Medical Biophysical Center of the Federal Medical Biological Agency

2. Medical Biological University of Innovations and Continuing Education of the Federal State Budgetary University the State Research Center — Burnasyan Federal Medical Biophysical Center; Ophthalmological Center of the Federal Medical and Biological Agency of the Russian Federation — Burnasyan Federal Medical Biophysical Center

Abstract

Insufficient blood supply, vascular dysregulation, perfusion pressure and endothelial dysfunction may account for the pathogenic mechanism. OCT angiography (OCTA) measurements have been reported to be useful for glaucoma diagnostics. OCTA microvasculature could serve as a potential biomarker for glaucoma diagnosis. One of the important criteria for the treatment of NTG is the reduction of IOP, which is achieved by both conservative methods of treatment and laser and surgical interventions. With timely diagnosis, control of IOP and monitoring of morphofunctional changes in the eyes with NTG, it becomes possible to suspend the development of glaucoma optic neuropathy and preserve the patient’s vision for a long time.

Publisher

PE Polunina Elizareta Gennadievna

Subject

Ophthalmology

Reference64 articles.

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3. Phelps CD, Corbett JJ. Migraine and low-tension glaucoma. A case-control study. Invest Ophthalmol Vis Sci. 1985 Aug;26(8):1105–1108.

4. Kurysheva NI, Irtegova EYu, Yasamanova AN. The role of endothelial dysfunction in glaucomatous optic neuropathy progression. Russian ophthalmological journal 2015;14(2):34–39 (In Russ.).

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