Appraisal of the Treatment Efficiency with Direct-Acting Anticoagulants in Ophthalmic Practice. Literature Review

Author:

Frolov M. A.1ORCID,Plyaskina U. S.1ORCID,Vorobyeva I. V.2ORCID,Frolov A. M.1ORCID,Biryukov V. V.1ORCID,Shallah S.1ORCID

Affiliation:

1. Peoples’ Friendship University of Russia

2. Peoples’ Friendship University of Russia; Russian Medical Academy of Continuous Professional Education

Abstract

Diabetic retinopathy (DR) is a disease that irrevocably leads to blindness, especially in the absence of proper monitoring and treatment. World statistics on its prevalence are not comforting. This pathology has always demanded and will continue to demand high attention from endocrinologists and ophthalmologists. In search of competent patient management, we have studied scientific papers on various treatment approaches with proven positive research results. We decided to analyze the drug Sulodexide, since in many studies it has proven to be a safe and effective direct anticoagulant with minimal side effects. As it turned out, Sulodexide is effective not only in relation to DR, but also in other pathologies of the fundus, which is described in this article.

Publisher

PE Polunina Elizareta Gennadievna

Subject

Ophthalmology

Reference25 articles.

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2. Dedov II, Shestakova MV, Vikulova OK, Zheleznyakova AV, Isakov MА. Epidemiological characteristics of diabetes mellitus in the Russian Federation: clinical and statistical analysis according to the Federal diabetes register data of 01.01.2021. Diabetes mellitus. 2021;24(3):204–221 (In Russ.). doi: 10.14341/DM12759.

3. Astakhov YuS, Tultseva SN, Umnikova TS. The use of tissue plasminogen activator and sulodexide for the treatment of retinal vein thrombosis. Regional circulation and microcirculation. 2002;1(2):45–49 (In Russ.).

4. Koledintsev MN, Verzin RA. The role of correction of the state of the endothelium and the basement membrane of the vascular wall in diabetic retinopathy. Еffective pharmacotherapy. 2015;43:10–13 (In Russ.).

5. Mokhort TV. The use of antithrombotic and vasoprotective agents in the treatment of vascular complications of diabetes mellitus. Healthcare (Minsk). 2011;4:21–26 (In Russ.).

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