Comparative Evaluation of The Clinical Efficacy of Various Technologies of Intraoperative Endolaserphotocoagulation in Patients with Proliferative Diabetic Retinopathy

Abstract

Purpose. To develop a safe and effective endolaserphotocoagulation technology used during vitreoretinal surgery in patients with advanced stage of proliferative diabetic retinopathy.Methods. We observed 88 patients (88 eyes) aged from 42 to 73 years (59 % women; 41 % men). All patients were divided into 2 equal groups based on age and gender, as well as preoperative functional results, a main group in which the developed technology of precision intraoperative endolaser coagulation was used (46 eyes), and a control group with a traditional technique of performing endolaser coagulation during vitreoretinal intervention (42 eyes). Results. Assessment of clinical and morphometric parameters in the main and control groups was carried out after 1, 3 and 6 months. The data obtained indicate a significant increase in BCVA (0.23 ± 0.05) in the group from the 3rd month of observation, no signs of increased IOP, as well as a decrease in retinal thickness in the foveal zone (up to 272.0 ± 27.3 μm) during the observation period up to 6 months. The study of the frequency of complications confirms the safety of the developed technology, which is confirmed by the low probability of developing rubeosis (1 case), neovascular glaucoma (1 case) and recurrence of retinal detachment in the main group of patients (2 cases) during a follow­up period of 6 months.Conclusion. The developed technology of precision endolaser coagulation is characterized by a higher (compared to the traditional technique) level of safety and clinical effectiveness, which is confirmed by the following main points: a greater likelihood of increasing BCVA; absence of increase in IOP during long­term observation, decrease in retinal thickness in the foveal zone starting from the 3rd month of observation; a significant reduction in the likelihood of postoperative complications.