Investigation on Molecular Structure, Vibrational Analysis and Thermodynamic Properties of 1-(2,6-dimethylmorpholine-4-yl-methyl)-3-methyl-4-[3-ethoxy-(4-benzenesulfonyloxy)-benzylidenamino]-4,5-dihydro-1H-1,2,4-triazol-5-one

Author:

Medetalibeyoğlu Hilal,Yüksek Haydar,Özdemir Gül

Publisher

Turkish Computational and Theoretical Chemistry

Subject

Materials Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Biochemistry, Genetics and Molecular Biology (miscellaneous),Molecular Medicine,Biochemistry

Reference35 articles.

1. References [1] F. Lopes, R. Capela, J.O. Goncaves, P.N. Horton, M.B. Hursthouse, J. Iley, C.M. Casimiro, J. Bom, R. Moreira, Amidomethylation of amodiaquine: antimalarial N-Mannich base derivativesTetrahedron Letters, 45 (2004) 7663-7666.

2. [2] B.S. Holla, B. Veerendra, M.K. Shivananda, B. Poojary, Synthesis characterization and anticancer activity studies on some Mannich bases derived from 1,2,4-triazoles, European Journal of Medicinal Chemistry, 38 (2003) 759-767.

3. [3] K. Kucukoglu, M. Gul, M. Atalay, E. Mete, C. Kazaz, O. Hanninen, H.I. Gul, Synthesis of some Mannich bases with dimethylamine and their hydrazones and evaluation of their cytotoxicity against Jurkat cells, Arzneimittelforschung 61 (2011) 366-371.

4. [4] H.I. Gul, J. Vepsalainen, M. Gul, E. Erciyas, O. Hanninen, Cytotoxic activities of mono and bis Mannich bases derived from acetophenone against Renca and Jurkat cells, Pharmaceutica Acta Helvetiae, 74(2000) 393-398.

5. [5] J.R. Dimmock, E. Erciyas, S.K. Raghavan, D.L. Kirkpatrick, Evaluation of the cytotoxicity of some Mannich bases of acetophenone against the EMT6 tumour, Pharmazie 45 (1990) 755-757.

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