Influence of the use of homoand probiotics in combination with fluorinated quinolones on the dynamics of protein metabolism in geese

Abstract

The effect of the combined use of homobiotics and probiotics with fluorinated quinolones on the change in the parameters of protein metabolism in geese is considered. Under the influence of schemes of use, including Vetom 13.1, Baytril and Vetom 1, there is no visible increase in the concentration of protein in the blood serum. When using a higher dosage of homobiotic at the beginning of the experiment, a decrease in this indicator is observed. When Baytril is withdrawn from this scheme and the homobiotic is replaced with a probiotic, the protein concentration in the blood serum does not decrease. During the research it was found that Baytril suppresses the protein-synthesizing potential of probionts Vetom 13.1 and Vetom 1. In geese of all experimental groups an increase in the concentration of albumin in the blood serum occurs. The most visible change was recorded when Vetom 13.1 was used together at a dosage of 50 mg / kg with Baytril and Vetom 1 at a similar dose. Regardless of the use of Baytril, the combination of Vetom 15.1 and Vetom 1.2 leads to an increase in the concentration of urea in the blood serum of geese, and Vetom 15.1 without other preparations increases this indicator only with cyclic use. The study of the schemes of using Vetom 13.1 shows that the concentration of urea is highly variable in its various combinations with other drugs. We found individual differences in the effect of Vetom 13.1 on the geese organism.