The life-history of Trypanosoma gambiense and Trypanosoma rhodesiense as seen in rats and guinea-pigs

Abstract

The researches recorded in this paper were undertaken at the suggestion of Major Ross, who wished me to investigate the parasitological aspect of the numerical cyclical development discovered by him and Dr. D. Thomson (1910) in the trypanosome occurring in a patient suffering from Sleeping Sickness contracted in Rhodesia, particularly as regards the possible connection of the latent bodies of Salvin-Moore and Breinl (1907) with that cycle. The investigations have been conducted in the Liverpool School of Tropical Medicine, under a grant from the Tropical Diseases Research Fund. A complete and generally accepted life cycle of Trypanosoma gambiense has yet to be written. The following paper is offered as a contribution to the solution of this difficult problem, and deals with that portion of the life history of the parasite which takes place in a Vertebrate host.