A critical study of experimental fever

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Abstract

The injection of solutions of salt into man and animals by the sub­-cutaneous or intravenous route has in recent years become a common practice. In many cases the procedure is followed by fever, as was shown in man by Kottmann (1) and by Schaps (2). If distilled water alone be injected in large quantities the same accident may happen, as shown (3) by E. Bergmann in 1868. In 1910 the injection of small quantities of water into animals was found (4) to have the same effect. The cause, however, of what are known as “water fever” and “salt fever” has till recently (5) not been satisfactorily explained, though many theories have been advanced.

Publisher

The Royal Society

Subject

General Medicine

Reference25 articles.

1. Bestimmung der Blutmenge b. Menschen u. Tier," ` Arch;Kottmann;Exp. Pathol. u. Pharmak.,',1906

2. Schaps " Saltz u. Zucker Injektion b. Sauglin. " `Berl. Klin. Woch. ' 1907 No. 19.

3. Bergmann E. " Ueber das durch Faulniss u. Entzundproducte erzeugte Fieber." *Petersburg Med. Zeitsch. ' 1868 p. 16.

4. Hort E. C. " Autotoxaemia and Infection " *Roy. Soc. Proc. ' 1910 vol. 82.

5. Hort and Penfold " The Dangers of Saline Injections " ` Brit. Med. Journ. December 16 1911 p. 1510.

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