On the fate of red blood corpuscles when injected into the circulation of an animal of the same species; with a new method for the determination of the total volume of the blood

Abstract

In a paper published last year the authors described a method by which it is possible to recognise the red blood corpuscles of any individual ox and to differentiate them from those of any other member of the same species. The method depends upon the fact that if a highly polyvalent isohæmolytic serum is treated repeatedly with the red blood corpuscles of any individual of the species for which the serum has been made, it entirely loses its hæmolytic action for the corpuscles of all other individuals of the same species. Such a serum therefore constitutes, so to speak, a specific reagent for the corpuscles of the individual for which it has been prepared, and by its means one is enabled to follow up and to identify these corpuscles even in the presence of corpuscles of other individuals.