Abstract
Remote-control stimulation has been applied to the hypothalamo-hypophysial region. Rabbits showed no ill-effects from the presence of the implanted unit for periods up to three years. Stimulation of the neurohypophysis in the conscious rabbit has been shown to cause: (
a
) inhibition of a water diuresis; (
b
) increase in urinary chlorides; (
c
) no change in the level of the blood sugar; (
d
) marked increase in the activity of the oestrous and oestrogenized uterus, whilst little effect was observed on the activity of the anoestrous or pseudo-pregnant uterus, or on the organ under the influence of progesterone. The anti-diuretic, chloruretic and oxytocic effects could be duplicated by intravenous injection of posterior lobe extracts. Stimulation caused a secretion which possessed less anti-diuretic than oxytocic activity, as compared with various posterior lobe extracts.
Subject
Industrial and Manufacturing Engineering,General Agricultural and Biological Sciences,General Business, Management and Accounting,Materials Science (miscellaneous),Business and International Management
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