Mathematical and computational modelling of skin biophysics: a review

Author:

Limbert Georges12ORCID

Affiliation:

1. National Centre for Advanced Tribology at Southampton (nCATS), Bioengineering Science Research Group, Faculty of Engineering and the Environment, University of Southampton, Southampton SO17 1BJ, UK

2. Biomechanics and Mechanobiology Laboratory, Biomedical Engineering Division, Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory 7925, Cape Town, South Africa

Abstract

The objective of this paper is to provide a review on some aspects of the mathematical and computational modelling of skin biophysics, with special focus on constitutive theories based on nonlinear continuum mechanics from elasticity, through anelasticity, including growth, to thermoelasticity. Microstructural and phenomenological approaches combining imaging techniques are also discussed. Finally, recent research applications on skin wrinkles will be presented to highlight the potential of physics-based modelling of skin in tackling global challenges such as ageing of the population and the associated skin degradation, diseases and traumas.

Funder

Engineering and Physical Sciences Research Council

Royal Society

Publisher

The Royal Society

Subject

General Physics and Astronomy,General Engineering,General Mathematics

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