Abstract
We have cloned a set of seven cDNAs corresponding to mRNAs induced by type I interferon in hum an cells, and are using these probes to characterize the response to interferon in detail. We have studied the kinetics of induction of each m RN A in three different hum an cell lines, the sensitivity of induction to cycloheximide, the effect of w ithdraw ing interferon and the response of a receptor-positive interferon-resistant cell line.
Subject
Industrial and Manufacturing Engineering,General Agricultural and Biological Sciences,General Business, Management and Accounting,Materials Science (miscellaneous),Business and International Management
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