Abstract
Our experimental results, as well as those of others, lead us to suggest the following steps in the dorsalization and axialization of theXenopusegg and embryo: (1) the spermaster determines the direction of rotation of the cortex relative to the deeper cytoplasm (endoplasm ); (2) the rotation of the cortex activates latent dorsalizingaxializing agents in the vegetal hemisphere. The extent of rotation determines the am ount of activation. The direction of rotation determines the location of the activated agents. (3) The activated agents determine the level of mesoderm-inducing activity of the vegetal cells cleaved from that cytoplasmic region. (4) The level of inducing activity determines at least the time at which marginal zone cells will begin gastrulation movements. (5) The time of its initiation of gastrulation may determine how anterior and dorsal a particular marginal zone cell can become.
Subject
Industrial and Manufacturing Engineering,General Agricultural and Biological Sciences,General Business, Management and Accounting,Materials Science (miscellaneous),Business and International Management
Cited by
29 articles.
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